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2'-Fluoro-2'-deoxycytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Fluoro-2'-deoxycytidine has been shown to inhibit Borna Disease virus replication and spread.
Michel Blandin.; Tran-Dinh Son.; Joseph C. Catlin.; Wilhelm Guschlbauer. Nucleoside conformations: 16. Nuclear magnetic resonance and circular dichroism studies on pyrimidine-2?-fluoro-2?-deoxyribonucleosides. Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 1974, 361, (3), 249-256.
Wohlrab, F.; Jamieson, A.T.; Hay, J.; Rolf Mengel.; Guschlbauer, W. The effect of 2?-fluoro-2?-deoxycytidine on herpes virus growth. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1985, 824, (3), 233-242.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.