J65687 GM 6001
CAS-Nummer
142880-36-2
Synonyme
Galardin
N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan methylamide
SDS
| Stock No. | Größe | Preis ($) | Menge | Verfügbarkeit |
|---|---|---|---|---|
| J65687-M^ | 1mg | 84,80 |
|
|
| J65687-#0 | 5mg | 305,00 |
|
|
GM 6001
MDL
MFCD03453614
Chemische Eigenschaften
Formel
C20H28N4O4
Molmasse
388.50
Form
Solid
Storage & Sensitivity
Keep Cold. Moisture Sensitive.
Löslichkeit
Soluble in DMSO, and 100% ethanol.
Anwendungen
GM 6001 is used to inhibits a wide variety of matrix metalloproteases with Kis in the nanomolar range. Active in a number of animal models of diseases where matrix metalloproteases are thought to be involved.
Bemerkungen
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Literaturverweise
Damian Grobelny.; Louis Poncz.; Richard E. Galardy. Inhibition of human skin fibroblast collagenase, thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids. Biochemistry. 1992, 31, (31), 7152-7154..
Chintda Santiskulvong.; Enrique Rozengurt. Galardin (GM 6001), a broad-spectrum matrix metalloproteinase inhibitor, blocks bombesin- and LPA-induced EGF receptor transactivation and DNA synthesis in rat-1 cells. Experimental Cell Research. 2003, 290, (2), 437-446..
Weitere Referenzen
Harmonized Tariff Code
2933.99
TSCA
No
Empfohlen
-
J64386
GM 6001, Negative Control
