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142880-36-2 - GM 6001 - Galardin - N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan methylamide - J65687 - Alfa Aesar

J65687 GM 6001

CAS-Nummer
142880-36-2
Synonyme
Galardin
N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan methylamide

Größe Preis ($) Menge Verfügbarkeit
1mg 78,66
5mg 323,42
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GM 6001

MDL
MFCD03453614

Chemische Eigenschaften

Formel
C20H28N4O4
Molmasse
388.50
Form
Solid
Sensitivität
Moisture Sensitive
Löslichkeit
Soluble in DMSO, and 100% ethanol.

Anwendungen

GM 6001 is used to inhibits a wide variety of matrix metalloproteases with Kis in the nanomolar range. Active in a number of animal models of diseases where matrix metalloproteases are thought to be involved.

Bemerkungen

Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literaturverweise

Damian Grobelny.; Louis Poncz.; Richard E. Galardy. Inhibition of human skin fibroblast collagenase, thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids. Biochemistry. 1992, 31, (31), 7152-7154..

Chintda Santiskulvong.; Enrique Rozengurt. Galardin (GM 6001), a broad-spectrum matrix metalloproteinase inhibitor, blocks bombesin- and LPA-induced EGF receptor transactivation and DNA synthesis in rat-1 cells. Experimental Cell Research. 2003, 290, (2), 437-446..

Weitere Referenzen

Harmonized Tariff Code
2933.99
TSCA
No

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