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Omi/HtrA2 Protease Inhibitor - High Temperature Requirement A2 Inhibitor I - 5-((5-(2-Nitrophenyl)furan-2-yl)methylene)-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione - J65767 - Alfa Aesar

J65767 Omi/HtrA2 Protease Inhibitor

CAS-Nummer
Synonyme
High Temperature Requirement A2 Inhibitor I
5-((5-(2-Nitrophenyl)furan-2-yl)methylene)-1,3-diphenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

Größe Preis ($) Menge Verfügbarkeit
10mg 154,00
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Omi/HtrA2 Protease Inhibitor

MDL
MFCD01000361

Chemische Eigenschaften

Formel
C27H17N3O5S
Molmasse
495.50
Form
Solid
Sensitivität
Light Sensitive
Löslichkeit
Soluble in DMSO at 5mg/ml

Anwendungen

A cell-permeable furfurylidine-thiobarbituric acid. Also small molecule/inhibitor is primarily used for Cancer applications.

Bemerkungen

Light Sensitive, store in dark. Keep the container tightly closed. Store away from oxidizing agent.

Literaturverweise

Srinivasa M. Srinivasula; Sanjeev Gupta; Pinaki Datta; ZhiJia Zhang; Ramesh Hegde; NaEun Cheong; Teresa Fernandes-Alnemri; and Emad S. Alnemri. Inhibitor of Apoptosis Proteins Are Substrates for the Mitochondrial Serine Protease Omi/HtrA2. The Journal of Biological Chemistry, 2003 , 27831469-31472.

Y Suzuki; K Takahashi-Niki; T Akagi; T Hashikawa; and R Takahashi. Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways. Cell Death and Differentiation, 2004, 11 208-216.

Weitere Referenzen

Harmonized Tariff Code
3504.00
TSCA
No

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