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J65894 Elastase Inhibitor III

Elastase inhibitor III, or MeOSuc-Ala-Ala-Pro-Val chloromethyl ketone, inhibits human leukocyte elastase (HLE). It is cell permeable and because of the chloromethyl ketone group, it irreversibly inhibits the enzyme. HLE is a serine protease found in the azurophilic granules of polymorphononuclear leukocytes. When then enzyme is released from the cell it can hydrolyze elastin and collagen. Increased HLE activity has been is associated with several diseases including rheumatoid arthritis and cystic fibrosis.

CAS-Nummer
65144-34-5
Synonyme
HLE Inhibitor
MeOSuc-AAPV-CMK

Stock No. Größe Preis ($) Menge Verfügbarkeit
J65894-#0 5mg 97,20
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Elastase Inhibitor III

MDL
MFCD00077136

Chemische Eigenschaften

Formel
C23H36ClN3O7
Molmasse
503.00
Form
Solid
Storage & Sensitivity
Store at -20°C. Moisture Sensitive.
Löslichkeit
Soluble in methanol or DMSO

Anwendungen

A potent irreversible inhibitor of human leukocyte elastase

Weitere Referenzen

Harmonized Tariff Code
3504.00
TSCA
No

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