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357649-93-5 - Histone Acetyltransferase Inhibitor IV, CPTH2 - HAT Inhibitor IV - Gcn5p Inhibitor - J65939 - Alfa Aesar

J65939 Histone Acetyltransferase Inhibitor IV, CPTH2

CAS-Nummer
357649-93-5
Synonyme
HAT Inhibitor IV
Gcn5p Inhibitor

Größe Preis ($) Menge Verfügbarkeit
5mg 77,10
10mg 123,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

Histone Acetyltransferase Inhibitor IV, CPTH2

MDL
MFCD02307488

Chemische Eigenschaften

Formel
C14H14ClN3S
Molmasse
291.80
Form
Solid
Sensitivität
Light Sensitive
Löslichkeit
Soluble in DMSO

Anwendungen

Histone acetylation plays an important role in regulating the chromatin structure and is tightly regulated by two classes of enzyme, histone acetyltransferases (HAT) and histone deacetylases (HDAC). Deregulated HAT and HDAC activity plays a role in the development of a range of cancers. Consequently, inhibitors of these enzymes have potential as anticancer agents.

Bemerkungen

Light Sensitive, store in dark. Keep the container tightly closed. Store away from oxidizing agent.

Literaturverweise

Franco Chimenti et. al. A novel histone acetyltransferase inhibitor modulating Gcn5 network: cyclopentylidene-[4-(4'-chlorophenyl)thiazol-2-yl)hydrazone. Journal of medicinal and pharmaceutical chemistry, 2009,52(2), 530-536.

Kaveri Sidhu; Vijay Kumar. c-ETS transcription factors play an essential role in the licensing of human MCM4 origin of replication. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1849,111319-1328.

GHS Gefahren- und Sicherheitshinweise

Sicherheitshinweise: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2934.10
TSCA
No

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