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12650-69-0 - Mupirocin, 92% - J66347 - Alfa Aesar

J66347 Mupirocin, 92%

CAS-Nummer
12650-69-0
Synonyme

Größe Preis ($) Menge Verfügbarkeit
50mg 285,00
100mg 456,00
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Mupirocin, 92%

MDL
MFCD01711620

Chemische Eigenschaften

Formel
C26H44O9
Molmasse
500.62
Form
Powder
Schmelzpunkt
77-78°
Siedepunkt
672°
Flammpunkt
>110°(230°F)
Löslichkeit
Soluble in DMSO or methanol. Sparingly soluble in water

Anwendungen

Mupirocin is involved in inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. It also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid.

Bemerkungen

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Typical working concentrations are in the range of 0.25µg/mL-0.39µg/mL.

Literaturverweise

Andrew E Simor; Tammy L Stuart; Lisa Louie; Christine Watt; Marianne Ofner-Agostini; Denise Gravel; Michael Mulvey; Mark Loeb; Allison McGeer; Elizabeth Bryce; Anne Matlow. Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals. Antimicrobial Agents and Chemotherapy. 2007, 51, (11), 3880-3886.

Gaston H.M. Vondenhoff; Arthur Van Aerschot. Aminoacyl-tRNA synthetase inhibitors as potential antibiotics. European Journal of Medicinal Chemistry. 2011, 46, (11), 5227-5236.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H303

May be harmful if swallowed.

Sicherheitshinweise: P312a

Weitere Referenzen

Merck
14,6302
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
RA6907000

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Chemikalien

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