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89786-04-9 - Tazobactam, 94% - J66483 - Alfa Aesar

J66483 Tazobactam, 94%

CAS-Nummer
89786-04-9
Synonyme

Tazobactam, 94%

MDL
MFCD00867002

Chemische Eigenschaften

Formel
C10H12N4O5S
Molmasse
300.29
Form
Powder
Schmelzpunkt
115-145°
Siedepunkt
77°
Flammpunkt
>110°(230°F)
Löslichkeit
Soluble in water

Anwendungen

Tazobactam is a drug is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms. It acts as a beta lactamase inhibitor. It is used in combination with piperacillin to broaden the spectrum of piperacillin antibacterial action. It is used as antibiotic in the treatment of nosocomial pneumonia caused by Pseudomonas aeruginosa.

Bemerkungen

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literaturverweise

Thomas P. Lodise; Ben Lomaestro and George L. Drusano. Piperacillin-Tazobactam for Pseudomonas aeruginosa Infection: Clinical Implications of an Extended-Infusion Dosing Strategy. Clin Infect Dis.2007, 44, (3), 357-363.

K Bush; C Macalintal; B A Rasmussen; V J Lee and Y Yang. Kinetic interactions of tazobactam with beta-lactamases from all major structural classes. Antimicrob. Agents Chemother.1993, 37, (4), 851-858.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2941.90
TSCA
No
RTECS
XI0191400

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