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61825-94-3 - Oxaliplatin - NSC 266046 - J66586 - Alfa Aesar

J66586 Oxaliplatin

CAS-Nummer
61825-94-3
Synonyme
NSC 266046

Größe Preis ($) Menge Verfügbarkeit
50mg 153,47
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Oxaliplatin

MDL
MFCD00866327

Chemische Eigenschaften

Formel
C8H14N2O4Pt
Molmasse
397.29
Form
Crystalline solid
Löslichkeit
Soluble in water with heating and/or sonication

Anwendungen

Oxaliplatin is an anti-tumor agent with activity against colorectal cancer. It shows antitumor activity in cell lines with acquired cisplatin resistance. It is used to treat cancer of the gullet (oesophagus). It is used as adjuvant therapy in patients who have had surgery to remove the cancer. It is used to treat testicular cancer.

Bemerkungen

Incompatible with heat and oxidizing agents.

Literaturverweise

D Khayat; M Gil-Delgado; E C Antoine; D Nizri; G Bastian. The role of irinotecan and oxaliplatin in the treatment of advanced colorectal cancer. Oncology (Williston Park, N.Y.).2001, 15, (4), 414-415.

Peter Draxler; Silke Doris Honsek; Liesbeth Forsthuber; Viktoria Hadschieff; Jürgen Sandkühler. VGluT3? primary afferents play distinct roles in mechanical and cold hypersensitivity depending on pain etiology. Journal of Neuroscience.2014, 34, (36), 12015-12028.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H334-H315-H319-H317-H335

May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. May cause respiratory irritation.

Sicherheitshinweise: P285-P261-P280-P305+P351+P338-P304+P340-P342+P311-P362-P312-P405-P501a

In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Harmonized Tariff Code
2843.90
TSCA
No
RTECS
TP2275850

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