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60-24-2 - 2-Mercaptoethanol, Electrophoresis Grade, 98+% - Thioethylene glycol - Thioglycol - J66742 - Alfa Aesar

J66742 2-Mercaptoethanol, Electrophoresis Grade, 98+%

CAS-Nummer
60-24-2
Synonyme
Thioethylene glycol
Thioglycol

Größe Preis ($) Menge Verfügbarkeit
250g 23,80
1000g 64,90
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2-Mercaptoethanol, Electrophoresis Grade, 98+%

MDL
MFCD00004890
EINECS
200-464-6

Chemische Eigenschaften

Formel
C2H6OS
Molmasse
78.13
Form
Liquid
Schmelzpunkt
-100°
Siedepunkt
156-158°
Flammpunkt
73°(163°F)
Dichte
1.114
Sensitivität
Air Sensitive & Hygroscopic
Löslichkeit
Fully miscible in water. Soluble in alcohol, ether, benzene, and other organic solvents.

Anwendungen

β-Mercaptoethanol can act as an enzyme reactivator in systems necessitating reduction for activation, and has been commonly used to reduce disulfide bonds in order to separate protein subunits for use in electrophoresis. This product can also be used to form o-Phthalaldehyde-beta-mercaptoethanol (OPAME), a fluorogenic reagent shown to detect amino acids based on its reaction with primary amines. More recently OPAME has been used to distinguish between ssDNA/dsDNA and even single base mismatches in the hybridization of DNA. It is widely used for retarding oxidation of biological compounds in solution.

Bemerkungen

Handle under dry protective gas. Store in cool condition. Incompatible with air, moisture, oxidizing agents.

Literaturverweise

Margaret L. Heidrick..; Linda C. Hendricks.; David E. Cook. Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice. Mechanisms of Ageing and Development. 1984, 27 (3),341-358 .

B. Tasheva.; G. Dessev. Artifacts in sodium dodecyl sulfate-polyacrylamide gel electrophoresis due to 2-mercaptoethanol.Anal. Biochem. 1983, 129 (1),98-102 .

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H227-H301-H310-H315-H318-H317-H335

Combustible liquid. Toxic if swallowed. Fatal in contact with skin. Causes skin irritation. Causes serious eye damage. May cause an allergic skin reaction. May cause respiratory irritation.

Sicherheitshinweise: P210u-P261-P301+P310a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. IF SWALLOWED: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,5869
Beilstein
773648
Gefahrenklasse
6.1
Verpackungsgruppe
II
Harmonized Tariff Code
2930.90
TSCA
Yes
RTECS
KL5600000

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