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Ceftiofur sodium is resistant to the antibiotic resistance enzyme beta-lactamase, and has activity against Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported. The bactericidal activity of ceftiofur results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins. The PBPs are transpeptidases which are vital in peptidoglycan biosynthesis. Therefore, their inhibition prevents this vital cell wall component from being properly synthesized.
Beate G. Rose.; Carol Kamps-Holtzapple.; Larry H. Stanker. Competitive Indirect ELISA for Ceftiofur Sodium and the Effect of Different Immunizing and Coating Antigen Conjugates. Bioconjugate Chem. 1995, 6, (5), 529-535.
Gefahrenhinweise (EU): H334-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
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