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It is used as a pharmaceutical intermediate.
Sakura, M, et al. Reaction of cyclohexa-1,2,3-triene with n, alpha -diphenyl-nitrone : formation of seven-membered cyclic amines via piradone derivatives.Heterocycles.,1999,51,(3), 547-556.
For an example of 1,3-dipolar cycloaddition with an alkene to give an isoxazolidine, see: Org. Synth. Coll., 5, 1124 (1973):
Similarly, regioselective addition to propiolic esters or alkynyl ketones gives isoxazolines: Tetrahedron, 44, 1247 (1988). The regioselectivity of 1,3-dipolar additions of nitrones with electron-deficient alkenes has been studied: J. Org. Chem., 49, 276 (1984).
Reviews: 1,3-Dipolar cycloadditions of nitrones: Synthesis, 205 (1975); The [3+2] nitrone-olefin cycloaddition reaction: Org. React., 36, 1 (1988); Synthetic applications of nitrones: Org. Prep. Proced. Int., 17, 25 (1985).