Methylsulfonylacetone is used as reactant for Stereoselective preparation of chiral cyclic ketones. It is used in the Preparation of poly-substituted pyridines. It aids for Gold-catalyzed Friedlander cyclocondensation reaction. It is used as reactant in Radical homoallylation reactions, multicomponent cyclocondensation with aldehydes and aminoazoles.
Smaranda C Marinescu; Toyoki Nishimata; Justin T Mohr; Brian M Stoltz. Homogeneous pd-catalyzed enantioselective decarboxylative protonation.Organic Letters.2008, 10 (6), 1039-1042.