Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

3128-06-1 - 4-Acetylbutyric acid, 97% - 5-Ketohexanoic acid - 5-Oxohexanoic acid - L03978 - Alfa Aesar

L03978 4-Acetylbutyric acid, 97%

CAS-Nummer
3128-06-1
Synonyme
5-Ketohexanoic acid
5-Oxohexanoic acid

Größe Preis ($) Menge Verfügbarkeit
5g 39,04
25g 129,78
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

4-Acetylbutyric acid, 97%

MDL
MFCD00004412
EINECS
221-511-7

Chemische Eigenschaften

Formel
CH3CO(CH2)3CO2H
Molmasse
130.14
Schmelzpunkt
12-14°
Siedepunkt
274-275°
Flammpunkt
>110°(230°F)
Dichte
1.100
Brechungsindex
1.4451
Löslichkeit
Slightly soluble in water, chloroform and methanol.

Anwendungen

4-Acetylbutyric acid is used in the synthesis of selective indomethacin analogues for AKR1C3 inhibition in the treatment of castrate-resistant prostate cancer. It is also used to prepare PARP inhibitors for the treatment of cancer.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.

Literaturverweise

Andy J. Liedtke; Adegoke O. Adenij; Mo Chen; Michael C. Byrns; Yi Jin; David W. Christianson; Lawrence J. Marnett and Trevor M. Penning. Development of Potent and Selective Indomethacin Analogues for the Inhibition of AKR1C3 (Type 5 17β-Hydroxysteroid Dehydrogenase/Prostaglandin F Synthase) in Castrate-Resistant Prostate Cancer.J. Med. Chem.2013, 56 (6), 2429-2446.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319

Causes skin irritation. Causes serious eye irritation.

Sicherheitshinweise: P280-P264-P305+P351+P338-P362-P321-P332+P313-P337+P313-P302+P352

Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash before reuse. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists: IF ON SKIN: Wash with plenty of soap and water.

Weitere Referenzen

Beilstein
385840
Harmonized Tariff Code
2918.30
TSCA
Yes

Empfohlen

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf