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Citraconic anhydride is used as a monomer for specialty unsaturated polyester resins. It is used to prepare bicyclic pyrrolidines, maleimides and co- and terpolymers. It is also used for the protection of N-terminal amino acids. Further, it is involved in the preparation of clothing ping acid and its amide. In addition to this, it is selectively used for the isolation of histidyl peptides.
Reagent for the protection of amino groups: Biochem. J., 109, 312 (1968).
Wang, L.; Wang, H.; Li, Y.; Tang, P. Total Synthesis of Schilancitrilactones?B and C. Angew. Chem. Int. Ed. 2015, 54 (19), 5732-5735.
Eddy, N. A.; Fenteany, G. Model studies directed to the synthesis of cucurbitacin I C/D rings. Tetrahedron Lett. 2015, 56 (36), 5079-5081.
Gefahrenhinweise (EU): H303-H311-H315-H319
May be harmful if swallowed. Toxic in contact with skin. Causes skin irritation. Causes serious eye irritation.
Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER/doctor if you feel unwell. Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.