Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

1423-60-5 - 3-Butyn-2-one, 98% - Ethynyl methyl ketone - L05527 - Alfa Aesar

L05527 3-Butyn-2-one, 98%

CAS-Nummer
1423-60-5
Synonyme
Ethynyl methyl ketone

Größe Preis ($) Menge Verfügbarkeit
1g 47,28
5g 144,20
25g 476,10
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

3-Butyn-2-one, 98%

MDL
MFCD00008775
EINECS
215-834-2

Chemische Eigenschaften

Formel
C4H4O
Molmasse
68.08
Siedepunkt
84-86°
Flammpunkt
-1°(30°F)
Dichte
0.870
Brechungsindex
1.4060
Löslichkeit
It is soluble in water.

Anwendungen

3-Butyn-2-one was used in the synthesis of clerodane diterpenoid (+/-)-sacacarin. It was used as substrate in stereoselective, conjugate arylation mediated by gallium(III) chloride leading to (E)-α,β-unsaturated ketones. 3-Butyn-2-one undergoes asymmetric double-Michael reaction with ortho-tosylamidophenyl malonate catalyzed by chiral aminophosphines to yield indolines2. It undergoes double Michael reaction with nitrogen-containing tethered diacid to give pipecolic acid derivatives. 3-Butyn-2-one, is used as a reactant with Dimethyl­ acetone-1,3-dicarboxyl­ate, under mild conditions to give a benzenoid product via a Michael addition - aldol cyclization process.

Bemerkungen

Stable under normal temperatures and pressures. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents.

Literaturverweise

H Monti.; G Audran.; G Léandri.; JP Monti. ZnI 2 Catalyzed [2+ 2] versus [3+ 2] cycloaddition of an allyltrimethylsilane with 3-butyn-2-one: Confirmation of a cyclobutene by-product formation. Tetrahedron letters. 1994, 35,(19), 3073-3076.

IH Um.; EJ Lee.; JS Min. Remarkable catalytic effect of H+ in Michael-type additions of anilines to 3-butyn-2-one. Tetrahedron letters. 2001, 57,(47), 9585-9589.

Reacts with Dimethyl­ acetone-1,3-dicarboxyl­ate, A14969, under mild conditions to give a benzenoid product via a Michael addition - aldol cyclization process: Synth. Commun., 28, 1525 (1998):

For a similar reaction, see Methyl­ 2-hexynoate, B23065.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H225-H300-H315-H335-H318

Highly flammable liquid and vapour. Fatal if swallowed. Causes skin irritation. May cause respiratory irritation. Causes serious eye damage.

Sicherheitshinweise: P210-P261-P280-P301+P310-P303+P361+P353-P305+P351+P338-P304+P340-P310-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
605353
Gefahrenklasse
3
Verpackungsgruppe
II
Harmonized Tariff Code
2914.19
TSCA
No

Empfohlen

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf