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27631-29-4 - 2,4-Dichloro-6,7-dimethoxyquinazoline, 97% - L06051 - Alfa Aesar

L06051 2,4-Dichloro-6,7-dimethoxyquinazoline, 97%

CAS-Nummer
27631-29-4
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 22,90
5g 62,90
25g 201,00
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2,4-Dichloro-6,7-dimethoxyquinazoline, 97%

MDL
MFCD00051733
EINECS
000-000-0

Chemische Eigenschaften

Formel
C10H8Cl2N2O2
Molmasse
259.09
Schmelzpunkt
175-179°
Sensitivität
Moisture Sensitive
Löslichkeit
Insoluble in water.

Anwendungen

2,4-Dichloro-6,7-dimethoxyquinazoline is used as an intermediate in the preparation of potential inhibitors of epidermal growth factor receptor kinases. It is also used as an intermediate in the preparation of terazosin.

Bemerkungen

Moisture Sensitive. Incompatible with oxidizing agents. Store in a cool, dry conditions in well sealed container.

Literaturverweise

T. H. Althuis; H. J. Hess. Synthesis and identification of the major metabolites of prazosin formed in dog and rat. J. Med. Chem.1977, 20, (1), 146-149.

Hans J. Hess; Timothy H. Cronin; Alexander Scriabine. Antihypertensive 2-amino-4(3H)-quinazolinones. J. Med. Chem.1968, 11, (1), 130-136.

For a review of the chemistry of quinazolines, see: Adv. Het. Chem., 24, 1 (1979).

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
190331
Harmonized Tariff Code
2933.59
TSCA
No

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