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6740-85-8 - 2-Chlorophenyl cyclopentyl ketone, 97% - (2-Chlorobenzoyl)cyclopentane - L06448 - Alfa Aesar

L06448 2-Chlorophenyl cyclopentyl ketone, 97%

CAS-Nummer
6740-85-8
Synonyme
(2-Chlorobenzoyl)cyclopentane

Größe Preis ($) Menge Verfügbarkeit
10g 49,30
50g 182,00
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2-Chlorophenyl cyclopentyl ketone, 97%

MDL
MFCD00038367
EINECS
229-802-0

Chemische Eigenschaften

Formel
C12H13ClO
Molmasse
208.69
Siedepunkt
130°/5mm
Flammpunkt
>100°(212°F)
Dichte
1.16
Brechungsindex
1.5470
Löslichkeit
Slightly miscible with chloroform and ethyl acetate.

Anwendungen

2-Chlorophenyl cyclopentyl ketone is used as a reagent in the preparation of bicyclic and polycyclic aromatic hydrocarbons. It acts as a pharmaceutical intermediate and also as an intermediate of ketamine.

Bemerkungen

Incompatible with oxidizing agents.

Literaturverweise

Li, Y.; Coller, J. K.; Hutchinson, M. R.; Klein, K.; Zanger, U. M.; Stanley, N. J.; Abell, A. D.; Somogyi, A. A. The CYP2B6* 6 allele significantly alters the N-demethylation of ketamine enantiomers in vitro. Drug Metab. Dispos. 2013, 41 (6), 1264-1272.

Jose, J.; Gamage, S. A.; Harvey, M. G.; Voss, L. J.; Sleigh, J. W.; Denny, W. A. Structure-activity relationships for ketamine esters as short-acting anaesthetics. Bioorg. Med. Chem. 2013, 21 (17), 5098-5106.

GHS Gefahren- und Sicherheitshinweise

Sicherheitshinweise: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
1873022
Harmonized Tariff Code
2914.79
TSCA
No

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