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alpha-Angelicalactone acts as acancer chemopreventive agent. It is used in the synthesis of glutathione and the activity of glutathione-S-transferase and UDP-glucunonosyltransferase detoxification enzymes in esophagus, stomach, intestine, and liver. It is used in oral care formulations to round out mint notes and in coffee flavors.
Richard A. Amos; John A. Katzenellenbogen. An efficient synthesis of .gamma.-methylene-.gamma.-butyrolactone (.alpha.'-angelicalactone). Application to the synthesis of deoxyobtusilactone and deoxyisoobtusilactone.J. Org. Chem.1978, 43 (4), 560-564.
Gefahrenhinweise (EU): H227-H303
Combustible liquid. May be harmful if swallowed.
Wear protective gloves and eye/face protection. In case of fire: Use for extinction: CO2, powder or water spray. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with local/regional/national/international regulations.