Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

3222-47-7 - 6-Methylnicotinic acid, 99% - 6-Methylpyridine-3-carboxylic acid - L08877 - Alfa Aesar

L08877 6-Methylnicotinic acid, 99%

CAS-Nummer
3222-47-7
Synonyme
6-Methylpyridine-3-carboxylic acid

Größe Preis ($) Menge Verfügbarkeit
1g 28,11
5g 89,30
25g 402,30
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

6-Methylnicotinic acid, 99%

MDL
MFCD00006341
EINECS
000-000-0

Chemische Eigenschaften

Formel
C7H7NO2
Molmasse
137.14
Schmelzpunkt
210-215°
Löslichkeit
Sparingly soluble in water.

Anwendungen

6-Methylnicotinic acid is an intermediate of the drug etoricoxib (a non- steroidal anti-inflammatory drug for the treatment of arthritis and osteoarthritis). It is also used as organic intermediates.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents. Store away from oxidizing agents.

Literaturverweise

Andreas Tinschert; Andreas Kiener; Klaus Heinzmann; A. Tschech. Isolation of new 6-methylnicotinic-acid-degrading bacteria, one of which catalyses the regioselective hydroxylation of nicotinic acid at position C2.Archives of Microbiology.1997, 168 355-361.

B.-M. Kukovec; Z. Popovic and G. Pavlovic. A new coordination mode of 6-methyl­nicotinic acid in trans-tetra­aquabis­(6-methyl­pyridine-3-carboxyl­ato-[kappa]O)cobalt(II) tetra­hydrate.Acta Cryst.2007, C63 m615-m617.

Dilithiation can be effected with LDA, allowing substitution at the 6-methyl group, as, for example carboxylation in the synthesis of methotrexate analogues: J. Med. Chem., 40, 370 (1997).

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
112049
Harmonized Tariff Code
2933.39
TSCA
No

Empfohlen

  • A11223

    6-Aminonicotinic acid, 98%
  • A12683

    Nicotinic acid, 99%
  • B22873

    Cystamine dihydrochloride, 97+%
  • L19845

    2-Aminopyridine-4-carboxylic acid, 96%
  • H33003

    2-Methyl-6-(trifluoromethyl)nicotinic acid, 97%

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf