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7152-15-0 - Ethyl isobutyrylacetate, 94% - Isobutyrylacetic acid ethyl ester - L09016 - Alfa Aesar

L09016 Ethyl isobutyrylacetate, 94%

CAS-Nummer
7152-15-0
Synonyme
Isobutyrylacetic acid ethyl ester

Größe Preis ($) Menge Verfügbarkeit
5g 37,17
25g 150,38
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Ethyl isobutyrylacetate, 94%

MDL
MFCD00009198
EINECS
230-491-9

Chemische Eigenschaften

Formel
C8H14O3
Molmasse
158.20
Schmelzpunkt
-9°
Siedepunkt
172-174°
Flammpunkt
53°(127°F)
Dichte
0.980
Brechungsindex
1.4265
Löslichkeit
Soluble in chloroform and methanol.

Anwendungen

Ethyl Isobutyrylacetate is used in the synthesis of piperazine derivatives as possible multireceptor atypical antipsychotics, affecting dopamine and serotonin receptor properties . Also used in the synthesis of pyrazinecarboxamide DGAT1 (diacylglycerol acyltransferase 1) inhibitors used in the treatment of obesity.

Bemerkungen

Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literaturverweise

A. Corma; V. Fornés; R.M. Martín-Aranda; F. Rey. Determination of base properties of hydrotalcites: Condensation of benzaldehyde with ethyl acetoacetate. Journal of Catalysis,1992, 134 (1), 58-65.

Akio Yamamoto; Shu Kambara. Structures of the Reaction Products of Tetraalkoxytitanium with Acetylacetone and Ethyl Acetoacetate. J. Am. Chem. Soc. 1957, 79 (16), 4344-4348.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H226

Flammable liquid and vapour.

Sicherheitshinweise: P210-P280-P240-P241-P233-P242-P243-P303+P361+P353-P403+P235-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Keep container tightly closed. Use only non-sparking tools. Take precautionary measures against static discharge. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
636726
Gefahrenklasse
3
Verpackungsgruppe
III
Harmonized Tariff Code
2921.42
TSCA
No

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