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Reatant in the synthesis of cyclic carbamates, cryptophycin analogues. Neopentanolamine with ammonia and hydrogen yeilds neopentyldiamine.
Bryan H. Norman,; Thomas Hemscheidt,; Richard M. Schultz,; Sherri L. Andis. Total Synthesis of Cryptophycin Analogues. Isosteric Replacement of the C-D Ester. J. Org. Chem. 1998, 63 (15), 5288-5294.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.