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7164-98-9 - 1-Phenylimidazole, 99% - L10579 - Alfa Aesar

L10579 1-Phenylimidazole, 99%

CAS-Nummer
7164-98-9
Synonyme

Größe Preis ($) Menge Verfügbarkeit
250mg 21,40
1g 55,70
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1-Phenylimidazole, 99%

MDL
MFCD00041204

Chemische Eigenschaften

Formel
C9H8N2
Molmasse
144.18
Schmelzpunkt
13°
Siedepunkt
142°/15mm
Flammpunkt
>110°(230°F)
Dichte
1.140
Brechungsindex
1.6000
Löslichkeit
Slightly soluble in water.

Anwendungen

1-phenylimidazole is a ligand for cytochrome P-450 and used as an inhibitor of microsomal oxidation. 1-Phenylimidazole is a suitable reagent used to investigate its effect on the citrulline formation by bovine brain nitric-oxide synthase. 1-Phenylimidazole is reported to be inhibitor of calmodulin-dependent nitric-oxide synthase from bovine brain and GHs pituitary cells.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literaturverweise

Christopher F. Wilkinson,; Krystyna Hetnarski,; Michael S. Denison. Selectivity of 1-phenylimidazole as a ligand for cytochrome P-450 and as an inhibitor of microsomal oxidation. Biochemical Pharmacology. 1983, 32 (6) 997-1003.

Sarvesh C. Vashishtha,; Edward M. Hawes,; Gordon McKay,; Denis J. McCann. Synthesis and Identification of the Quaternary Ammonium-Linked Glucuronide of 1-Phenylimidazole in Human Liver Microsomes and Investigation of the Human UDP-Glucuronosyltransferases Involved. Drud metabolism and disposition. 2000, 28 (9), 1009-1013.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319

Causes skin irritation. Causes serious eye irritation.

Sicherheitshinweise: P280a-P264-P305+P351+P338-P321-P332+P313-P337+P313

Wear protective gloves and eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists:

Weitere Referenzen

Beilstein
112356
Harmonized Tariff Code
2933.29
TSCA
No

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