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6055-19-2 - Cyclophosphamide monohydrate, 97+% - Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester - Cyclophosphane - L11508 - Alfa Aesar

L11508 Cyclophosphamide monohydrate, 97+%

CAS-Nummer
6055-19-2
Synonyme
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
Cyclophosphane

Größe Preis ($) Menge Verfügbarkeit
1g 38,52
5g 96,41
25g 280,80
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Cyclophosphamide monohydrate, 97+%

MDL
MFCD00149395
EINECS
200-015-4

Chemische Eigenschaften

Formel
C7H15Cl2N2O2P•H2O
Molmasse
279.10 (261.09anhy)
Schmelzpunkt
51-53°
Flammpunkt
113°(235°F)
Löslichkeit
Soluble in water. Slightly soluble ethanol, benzene, ethylene glycol, carbon tetrachloride, dioxane, ether, acetone, alcohol and chloroform.

Anwendungen

Cyclophosphamide monohydrate is used to treat cancers, autoimmune disorders and AL amyloidosis. It is a nitrogen mustard alkylating agent and reacts with deoxyribonucleic acid (DNA) to get its alkylated derivative. It is also involved in cancer research as a tool that induces apoptosis in tumor cells.

Bemerkungen

Special handling precautions required. View MSDS prior to purchase, available online at www.alfa.comStore in cool place. Moisture and light senstive. Incompatible with strong oxidizing agents, strong acids and strong bases.

Literaturverweise

Musa, M.; Ali, K. M.; Kannan, T. P.; Azlina, A.; Omar, N. S.; Chatterji, A.; Mokhtar, K. I. Effects of Perivitelline Fluid Obtained from Horseshoe Crab on The Proliferation and Genotoxicity of Dental Pulp Stem Cells. Cell J. 2015, 17 (2), 253-263.

Chien, M. Y.; Lin, Y. T.; Peng, F. C.; Lee, H. J.; Chang, J. M.; Yang, C. M.; Chen, C. H. Gastroprotective potential against indomethacin and safety assessment of the homology of medicine and food formula cuttlebone complex. Food Funct. 2015, 6 (8), 2803-2812.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H301-H340-H350-H360

Toxic if swallowed. May cause genetic defects. May cause cancer. May damage fertility or the unborn child.

Sicherheitshinweise: P201-P281-P264-P270-P301+P310-P308+P313-P321-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF exposed or concerned: Get medical advice/attention. Specific treatment (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,2747
Beilstein
8167897
Gefahrenklasse
6.1
Verpackungsgruppe
III
Harmonized Tariff Code
2934.99
TSCA
No
RTECS
RP6157750

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