Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

98-79-3 - (S)-(-)-2-Pyrrolidinone-5-carboxylic acid, 98+% - L-Pyroglutamic acid - H-Pyr-OH - L11711 - Alfa Aesar

L11711 (S)-(-)-2-Pyrrolidinone-5-carboxylic acid, 98+%

CAS-Nummer
98-79-3
Synonyme
L-Pyroglutamic acid
H-Pyr-OH

Größe Preis ($) Menge Verfügbarkeit
25g 22,20
100g 52,70
500g 199,00
Zum Warenkorb hinzufügen Zur Angebotsanfrage hinzufügen Artikel anzeigen

(S)-(-)-2-Pyrrolidinone-5-carboxylic acid, 98+%

MDL
MFCD00005272
EINECS
202-700-3

Chemische Eigenschaften

Formel
C5H7NO3
Molmasse
129.12
Schmelzpunkt
158-162°
Löslichkeit
Soluble in water (10-15% at 20°C), alcohol, acetone, dimethyl sufoxide and methanol.

Anwendungen

(S)-(-)-2-Pyrrolidinone-5-carboxylic acid is used as a building block for pharmaceuticals and asymmetric synthesis. It Is also used as a resolving agent for chiral bases and in an efficient synthesis of quinolizidine and indolizidine alkaloids.

Bemerkungen

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literaturverweise

Liang Wang.; Xiangju Meng.; Bin Wang.; Wenyang Chi.; Feng-Shou Xiao. Pyrrolidone-modified SBA-15 supported Au nanoparticles with superior catalytic properties in aerobic oxidation of alcohols. Chem. Commun. 2010, 46 (27), 5003-5005.

Liang Wang.; Hong Wang.; Prokop Hapala.; Longfeng Zhu.; Limin Renb, Xiangju Meng.; James P. Lewis.; Feng-Shou Xiao. Superior catalytic properties in aerobic oxidation of olefins over Au nanoparticles on pyrrolidone-modified SBA-15. Journal of Catalysis. 2011, 281 (1), 30-393.

Resolving agent for chiral bases: Helv. Chim. Acta, 41, 181 (1958). Versatile chiral starting material:

Reduction to the alcohol followed by reaction with benzaldehyde gives a bicyclic lactam which is a useful chiral synthon: J. Org. Chem., 51, 3140 (1986); Tetrahedron Lett., 32, 1379 (1991):

For use in an efficient synthesis of quinolizidine and indolizidine alkaloids, see: J. Org. Chem., 60, 717 (1995).

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,8001
Beilstein
82132
Harmonized Tariff Code
2933.79
TSCA
Yes
RTECS
TW3710000

Empfohlen

  • A10192

    Quinaldic acid, 98%
  • A13064

    tert-Butyldimethylchlorosilane, 97%
  • A14708

    Di-tert-butyl dicarbonate, 97+%
  • B24678

    (R)-(+)-2-Pyrrolidinone-5-carboxylic acid, 98+%
  • 44816

    Mercury(II) bromide, ACS

Kürzlich angesehen

Chemikalien

Life science

Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf