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1122-28-7 - 4,5-Dicyanoimidazole, 98+% - Imidazole-4,5-dicarbonitrile - L12215 - Alfa Aesar

L12215 4,5-Dicyanoimidazole, 98+%

CAS-Nummer
1122-28-7
Synonyme
Imidazole-4,5-dicarbonitrile

Größe Preis ($) Menge Verfügbarkeit
5g 27,19
25g 92,08
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4,5-Dicyanoimidazole, 98+%

MDL
MFCD00005194
EINECS
214-344-6

Chemische Eigenschaften

Formel
C5H2N4
Molmasse
118.10
Schmelzpunkt
173-177°
Löslichkeit
Soluble in Acetonitrile: 1.8g/10ml, DMSO, Methanol.

Anwendungen

4,5-Dicyanoimidazole is used in activation of nucleoside phosphoramidites during solid-phase oligonucleotide synthesis, and synthesis of nucleoside phosphoramidites, synthesis of novel nucleosides. It is often used as an alternative to tetrazole.

Bemerkungen

Store in a cool, dry conditions in well sealed container. Incompatible with oxidizing agents.

Literaturverweise

Chandra Vargeese; Jeff Carter; John Yegge; Shira Krivjansky; Alecia Settle; Eric Kropp; Kent Peterson and Wolfgang Pieken. Efficient activation of nucleoside phosphoramidites with 4,5-dicyanoimidazole during oligonucleotide synthesis. Nucl. Acids Res.1998, 26, (4), 1046-1050.

Paul G. Apen; Paul G. Rasmussen. Synthesis and properties of new derivatives of 4,5-dicyanoimidazole and 4,4',5,5'-tetracyano-2,2'-biimidazole. J. Am. Chem. Soc.1991, 113, (16), 6178-6187.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H318-H315-H302-H335

Causes serious eye damage. Causes skin irritation. Harmful if swallowed. May cause respiratory irritation.

Sicherheitshinweise: P280h-P305+P351+P338

Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Weitere Referenzen

Beilstein
118208
Harmonized Tariff Code
2933.29
TSCA
No

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