1-Naphthyl isothiocyanate is a tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bile duct hyperplasia and biliary cirrhosis chronically, with changes in hepatocyte function.
Matthew Quinn; Yoshiyuki Ueno; Hae Yong Pae; Li Huang; Gabriel Frampton; Cheryl Galindo; Heather Francis; Darijana Horvat; Matthew McMillin; Sharon Demorrow. American Journal of Physiology - Gastrointestinal and Liver Physiology.2012, 302, (1), G182-G193.
Cen Guo; Lei He; Dan Yao; Jiye A; Bei Cao; Jin Ren; Guangji Wang; Guoyu Pan. Alpha-naphthylisothiocyanate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes. Toxicology Letters.2014, 224, (1), 93-100.
Gefahrenhinweise (EU): H301-H311-H331-H314-H318
Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
IF SWALLOWED: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.