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Fluorescein is used as a fluorescent tracer for many applications including in a type of dye laser as the gain medium, in forensics and serology to detect latent blood stains and in dye tracing. It is used to localise multiple muscular ventricular septal defects during open heart surgery and confirm the presence of any residual defects. It is applied to teeth to reveal plaque.
Akram, A. C.; Noman, S.; Moniri-Javid, R.; Gizicki, J. P.; Reed, E. A.; Singh, S. B.; Basu, A. S.; Banno, F.; Fujimoto, M.; Ram, J. L. Development of an automated ballast water treatment verification system utilizing fluorescein diacetate hydrolysis as a measure of treatment efficacy. Water Res. 2015, 70, 404-413.
Tichauer, K. M.; Guthrie, M.; Hones, L.; Sinha, L.; St. Lawrence, K.; Kang-Mieler, J. J. Quantitative retinal blood flow mapping from fluorescein videoangiography using tracer kinetic modeling. Opt. Lett. 2015, 40 (10), 2169-2172.
Gefahrenhinweise (EU): H319
Causes serious eye irritation.
Wear eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.