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4767-03-7 - 2,2-Bis(hydroxymethyl)propionic acid, 98+% - L14014 - Alfa Aesar

L14014 2,2-Bis(hydroxymethyl)propionic acid, 98+%

CAS-Nummer
4767-03-7
Synonyme

Größe Preis ($) Menge Verfügbarkeit
100g 24,75
500g 60,03
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2,2-Bis(hydroxymethyl)propionic acid, 98+%

MDL
MFCD00004199
EINECS
225-306-3

Chemische Eigenschaften

Formel
C5H10O4
Molmasse
134.13
Schmelzpunkt
187-191°
Sensitivität
Hygroscopic
Löslichkeit
Soluble in acetone (slightly), methanol, and water. Insoluble in benzene.

Anwendungen

2,2-Bis(hydroxymethyl)propionic acid is used in the synthesis and characterization studies of polyurethane dispersion modified with polymethylsiloxane (Si-PUD) and its nanocomposites incorporated with clays1.2,2-Bis(hydroxymethyl)propionic acid based dendrimers have potent applications as delivery systems for potent anticancer drugs such as cisplatin and doxorubicin, as well as agents for both boron neutron capture therapy and photodynamic therapy Simple derivatives of this acid have been used to construct dendritic architectures via the “click” azide-acetylene cycloaddition.

Bemerkungen

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. It is hygroscopic in nature.

Literaturverweise

Elizabeth R. Gillies.; Jean M.J. Fréchet. Dendrimers and dendritic polymers in drug delivery. Drug Discovery Today. 2005, 10 (1), 35-43.

Ihre H.; Hult A. Double-stage convergent approach for the synthesis of functionalized dendritic aliphatic polyesters based on 2, 2-bis (hydroxymethyl) propionic acid. Macromolecules. 1999, 31 (13), 4061-4068.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Sicherheitshinweise: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,3253
Beilstein
1756385
Harmonized Tariff Code
2918.19
TSCA
Yes

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