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a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists. 5?-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase, an activator of phosphorylase b in the polymerization reaction for the synthesis of branched polysaccharides, a reagent in the synthesis of adenosine-5?-phosphoimidazolide, an inhibitor of endogenous NMN adenylyltransferase (NMNAT) activity that converts NMN to NAD+.
Markus Hafner; Pablo Landgraf; Janos Ludwig; Amanda Rice; Tolulope Ojo; Carolina Lin; Daniel Holoch; Cindy Lim; Thomas Tuschl. Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing. Methods. 2008, 44, (1), 3-12.
Marianne Suter; Uwe Riek; Roland Tuerk; Uwe Schlattner; Theo Wallimann; Dietbert Neumann. Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase. Journal of Biological Chemistry. 2006, 281, (43), 32207-32216.