I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
4,5-Dimethoxy-2-nitrobenzyl chloroformate is used as a reagent for protection of amines, for use in N-protection of bases in nucleotide synthesis, photochemical protecting groups in organic synthesis. It is used as pharmaceutical intermediate.
P Roy, Z Rajfur; D Jones; G Marriott; L Loew; K Jacobson. Local photorelease of caged thymosin beta4 in locomoting keratocytes causes cell turning. Journal of Cell Biology. 2001, 153, (5), 1035-1048.
Adam Frankel; Steven W Millward; Richard W Roberts. Encodamers: Unnatural Peptide Oligomers Encoded in RNA. Chemistry & Biology. 2003, 10, (11), 1043-1050.
Reagent for protection of amines. The group is readily cleaved photolytically: Tetrahedron Lett., 29, 65 (1988). For use in N-protection of bases in nucleotide synthesis, see: J. Org. Chem., 64, 6319 (1999). For reviews of photochemical protecting groups in organic synthesis, see: Synthesis, 1 (1980); Org. Photochem., 9, 225 (1987).
Gefahrenhinweise (EU): H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Obtain special instructions before use. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.