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Methacryloyl chloride is used in the preparation of polymeric materials. It reacts with L-histidine and forms functional monomer. It is also used to prepare monomer 2-methacrylamido-caprolactam, amide monomers by amidation.
Warneke, J.; Wang, Z.; Zeller, M.; Leibfritz, D.; Plaumann, M.; Azov, V. A. Methacryloyl chloride dimers: from structure elucidation to a manifold of chemical transformations. Tetrahedron 2014, 70 (37), 6515-6521.
Dong, L. T.; Zhu, J.; Xiao, W. F. Synthesis of Graft Copolymer by Using Acrylamide and Methacryloyl Chloride Guar Gum and its Adsorption Behavior to Metal Ions. Adv. Mat. Res. 2012, 535, 1087-1090.
Gefahrenhinweise (EU): H225-H302-H330-H314-H318
Highly flammable liquid and vapour. Harmful if swallowed. Fatal if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.