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A novel derivative of 1-phenyl-2-pyrrolidinone, blebbistatin, inhibits non-muscle myocin II activity with high specificity.
Mark S Duxbury; Stanley W Ashley; Edward E Whang. Inhibition of pancreatic adenocarcinoma cellular invasiveness by blebbistatin: a novel myosin II inhibitor. Biochemical and Biophysical Research Communications.2004, 313(4), 992-997.
John S Allingham; Robert Smith; & Ivan Rayment. The structural basis of blebbistatin inhibition and specificity for myosin II. Nature Structural & Molecular Biology.2005, 12378 - 379.