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Arbutin, a glycosylated hydroquinone, is used in studies on melanin biosynthesis and as an inhibitor to identify, differentiate and characterize tyrosinase(s). Also used in sed as a skin-lightening agent in cosmetic products.
Hsiou-Yu Ding; Te-Sheng Chang; Hung-Chang Shen; Sorgan Shou-Ku Tai. Murine tyrosinase inhibitors from Cynanchum bungei and evaluation of in vitro and in vivo depigmenting activity. Experimental Dermatology.2011, 20(9), 720-724.
Sang Mi An; Jae-Sook Koh; Yong Chool Boo. p-coumaric acid not only inhibits human tyrosinase activity in vitro but also melanogenesis in cells exposed to UVB. Phytotherapy Research.2010, 24(8), 1175-1180.