Used for solubilizing membrane proteins during isolation and purification.Polysorbate 20 is used as a wetting agent in flavored mouth drops. It acts as a washing agent in Western blots and ELISAs and prevents antibody binding. It is a solubilizing agent of membrane proteins. In pharmaceutical chemistry, it is used as an excipient to stabilize emulsions and suspensions. Further, it is used as a dispersing agent, stabilizer, lubricator and also used in creams, salves, ointments, protective creams, balms, pomades, lipsticks, mascaras and glosses.
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Siska, C. C.; Pierini, C. J.; Lau, H. R.; Latypov, R. F.; Fesinmeyer, R. M.; Litowski, J. R. Free Fatty Acid Particles in Protein Formulations, Part 2: Contribution of Polysorbate Raw Material. J. Pharm. Sci. 2015, 104 (2), 447-456.