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(tert-Butoxycarbonylmethylene)triphenylphosphorane is a chemical used in the synthesis of aldose reductase inhibitors, a podophyllotoxin derivative and tautomycin, a podophyllotoxin derivative and tautomycin. It Is also used in medicinal chemistry.
B L Mylari.; W J Zembrowski.; T A Beyer, C E Aldinger.; T W Siegel. Orally active aldose reductase inhibitors: indazoleacetic, oxopyridazineacetic, and oxopyridopyridazineacetic acid derivatives. Langmuir. 1992, 35 (12), 2155-2162.
Rabindra Rej.; Dieu Nguyen.; Brian Go.; Samuel Fortin.; Jean-François Lavallée. Total Synthesis of Cryptophycins and Their 16-(3-Phenylacryloyl) Derivatives. J. Org. Chem. 1996, 61 (18), 6289-6295.
Gefahrenhinweise (EU): H301-H319-H317-H373
Toxic if swallowed. Causes serious eye irritation. May cause an allergic skin reaction. May cause damage to organs through prolonged or repeated exposure.
Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.