I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
Ethyl cyanoformate is used as reagent in the preparation of N-substituted amindinoformic acid and ethyl-4-quinazoline -2-carboxylate.
Reagent for ethoxycarbonylation of enolate anions: Tetrahedron, 43, 45 (1987). In the presence of ZnCl2, active methylene compounds are converted to ɑ-amino acrylate esters: Tetrahedron. Lett, 2525 (1979).
North, M.; Urwin, S. Kinetics and mechanism of base catalysed ethyl cyanoformate addition to aldehydes. Tetrahedron 2014, 70 (40), 7100-7105.
Ji, N., Yao, L.; He, W.; Li, Y. Bifunctional Schiff base/Ti (IV) catalysts for enantioselective cyanoformylation of aldehydes with ethyl cyanoformate. Appl. Organomet. Chem. 2013, 27 (4), 209-213.
Gefahrenhinweise (EU): H226-H300-H310-H330-H314-H318
Flammable liquid and vapour. Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
IF SWALLOWED: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.