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(R)-(-)-1,2,3,4-Tetrahydro-1-naphthylamine is a important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field. Chiral amines play an important role in stereoselective organic synthesis. They are used directly as resolving agents, building blocks or chiral auxiliaries.
Min Qiu.; Xiang-Ping Hu.; Jia-Di Huang.; Dao-Yong Wang.; Jun Deng.; Sai-Bo Yu.; Zheng-Chao Duan.; Zhuo Zheng. Modular Phosphine-Aminophosphine Ligands Based on Chiral 1,2,3,4-Tetrahydro-1-naphthylamine Backbone: A New Class of Practical Ligands for Enantioselective Hydrogenations. Advanced Synthesis & Catalysis. 2008, 350 (17), 2683-2689.
Min Qiu.; Xiang-Ping Hu.; Dao-Yong Wang.; Jun Deng.; Jia-Di Huang.; Sai-Bo Yu.; Zheng-Chao Duan.; Zhuo Zheng. Chiral 1,2,3,4-Tetrahydro-1-naphthylamine-Derived Phosphine-Phosphoramidite Ligand (THNAPhos): Application in Highly Enantioselective Hydrogenations of Functionalized C[DOUBLE BOND]C Bonds. Langmuir. 2008, 350 (9), 1413-1418.
Gefahrenhinweise (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.