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(S)-(-)-1-(2-Naphthyl)ethylamine is used in asymmetric synthesis. It is also used in the preparation of thiourea compounds using chiral amine, which is used as a bifunctional catalyst for the Strecker and nitro-Michael reactions. Further, it acts as a chiral building block and chiral resolution reagent.
Shcherbakova, E. G.; Minami, T.; Brega, V.; James, T. D.; Anzenbacher, P. Determination of Enantiomeric Excess in Amine Derivatives with Molecular Self-Assemblies. Angew. Chem. Int. Ed. 2015, 54 (24), 7130-7133.
Polindara-García, L. A.; Montesinos-Miguel, D.; Vazquez, A. An efficient microwave-assisted synthesis of cotinine and iso-cotinine analogs from an Ugi-4CR approach. Org. Biomol. Chem. 2015, 13 (34), 9065-9071.
Gefahrenhinweise (EU): H301-H311-H314-H318
Toxic if swallowed. Toxic in contact with skin. Causes severe skin burns and eye damage. Causes serious eye damage.
Do not breathe dusts or mists. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.