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It is used in an efficient synthesis of SK-658 and its analogs as potent histone deacetylase inhibitors.
Giovanni B. Giovenzana, et al. Polycyclic compounds from aminopolyols and α-dicarbonyls: structure and application in the synthesis of exoditopic ligands.Org. Biomol. Chem.,2005,3(8), 1489-1494.
Masumi Asakawa, et al. Structure-Reactivity Relationship in Interlocked Molecular Compounds and in Their Supramolecular Model Complexes.Org. Biomol. Chem.,2003,11(7), 1153-1160.
Gefahrenhinweise (EU): H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Obtain special instructions before use. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.