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459-04-1 - 4-Fluorophenylacetyl chloride, 97% - L19235 - Alfa Aesar

L19235 4-Fluorophenylacetyl chloride, 97%

CAS-Nummer
459-04-1
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 43,67
5g 121,50
25g 424,80
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4-Fluorophenylacetyl chloride, 97%

MDL
MFCD00674181
EINECS
000-000-0

Chemische Eigenschaften

Formel
C8H6ClFO
Molmasse
172.59
Siedepunkt
60°/8mm
Flammpunkt
107°(224°F)
Dichte
1.259
Brechungsindex
1.5120
Sensitivität
Moisture Sensitive
Löslichkeit
Miscible with dichloromethane.

Anwendungen

4-Fluorophenylacetyl chloride is used as an acylating agent in organic synthesis. It is used to prepare monoacylated pyrazolidine by reacting with pyrazolidine. It is also used in the preparation of N-acyl isothiouronium chloride.

Bemerkungen

Moisture Sensitive. Store in a cool place. Incompatible with water, alcohols, oxidizing agents and strong bases.

Literaturverweise

Kalalbandi, V. K. A.; Seetharamappa, J.; Katrahalli, U. Synthesis, crystal studies and in vivo anti-hyperlipidemic activities of indole derivatives containing fluvastatin nucleus. RSC Adv. 2015, 5 (48), 38748-38759.

Garazd, M. M.; Garazd, Y. L.; Ogorodniichuk, A. S.; Khilya, V. P. Modified coumarins. 29. Synthesis of structural analogs of natural 6-arylfuro[3,2-g]chromen-7-ones. Chem. Nat. Compd. 2009, 45 (2), 158-163.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Sicherheitshinweise: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Beilstein
972148
Gefahrenklasse
8
Verpackungsgruppe
II
Harmonized Tariff Code
2916.39
TSCA
No

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