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Isoquinoline-1-carbonitrile is used as starting reagent in the syntheses of imidazo[5,1-a]isoquinolines. It is also used as intermediate in organic syntheses.
Sharmistha Dutta Choudhury.; Samita Basu. Interaction of 4-nitroquinoline-1-oxide with indole derivatives and some related biomolecules: a study with magnetic field. Journal of Physical Chemistry. 2006, 110 (17), 8850-8855.
Mickaël Pauvert.; Sylvain C. Colleta.; Marie-Jo Bertranda.; André Y. Guingant.; Michel Evain. Synthesis of chiral N-protected 1,2-dihydro-quinoline-2-carbonitrile and 1,2-dihydro-isoquinoline-1-carbonitrile via an asymmetric Reissert reaction. Tetrahedron Letters. 2005, 46 (17), 2983-2987.
Gefahrenhinweise (EU): H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.