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71-44-3 - Spermine, 97% - Neuridine - Musculamine - L19562 - Alfa Aesar

L19562 Spermine, 97%

CAS-Nummer
71-44-3
Synonyme
Neuridine
Musculamine

Größe Preis ($) Menge Verfügbarkeit
1g 40,40
5g 134,00
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Spermine, 97%

MDL
MFCD00008215
EINECS
200-754-2

Chemische Eigenschaften

Formel
C10H26N4
Molmasse
202.35
Schmelzpunkt
28-30°
Siedepunkt
150°/5mm
Flammpunkt
>110°(230°F)
Sensitivität
Air Sensitive & Hygroscopic
Löslichkeit
Soluble in chloroform, methanol, water and lower alcohols. Insoluble in ether, benzene and petroleum ether.

Anwendungen

Binds to the polyamine modulatory site of NMDA Spermine is essential for both normal and neoplastic tissue growth. It is involved in the modulation of calcium-dependent immune processes. It plays an important role in cellular proliferation and differentiation as well as inhibits neuronal nitric oxide synthase (nNOS).

Bemerkungen

Air sensitive and hygroscopic. Store in a cool place. Incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.

Literaturverweise

Bailey, D.; Kirby, B. P.; Atkinson, J.; Fixon-Owoo, S.; Henman, M. C.; Shaw, G. G.; Doyle, K. M. Hydroxycinnamic acid amide derivatives of polyamines reverse spermine-induced CNS excitation. Pharmacol. Biochem. Behav. 2015, 133, 57-64.

Mo, H.; Wang, X.; Zhang, Y.; Zhang, G.; Zhang, J.; Ma, Z. Cotton polyamine oxidase is required for spermine and camalexin signalling in the defence response to Verticillium dahliae. Plant J. 2015, 83 (6), 962-975.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Sicherheitshinweise: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a

Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Merck
14,8743
Beilstein
1751791
Gefahrenklasse
8
Verpackungsgruppe
III
Harmonized Tariff Code
2921.29
TSCA
Yes
RTECS
EJ7175000

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