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351003-45-7 - 2-Bromo-4-fluorobenzenesulfonyl chloride, 97% - L19713 - Alfa Aesar

L19713 2-Bromo-4-fluorobenzenesulfonyl chloride, 97%

CAS-Nummer
351003-45-7
Synonyme

Größe Preis ($) Menge Verfügbarkeit
1g 43,47
5g 184,37
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2-Bromo-4-fluorobenzenesulfonyl chloride, 97%

MDL
MFCD03094149
EINECS
000-000-0

Chemische Eigenschaften

Formel
C6H3BrClFO2S
Molmasse
273.51
Siedepunkt
264-265°
Dichte
1.870
Brechungsindex
1.5780
Sensitivität
Moisture Sensitive
Löslichkeit
Hydrolyzes in water.

Anwendungen

2-Bromo-4-fluorobenzenesulfonyl chloride is used as a pharmaceutical intermediate.

Bemerkungen

Moisture sensitive. Store away from oxidizing agents, water/ moisture, bases.

Literaturverweise

Ashit K. Ganguly; Sesha S. Alluri; Danielle Caroccia; Dipshikha Biswas; Chih-Hung Wang; Eunhee Kang; Yong Zhang; Andrew T. McPhail; Steven S. Carroll; Christine Burlein; Vandna Munshi; Peter Orth and Corey Strickland. Design, Synthesis, and X-ray Crystallographic Analysis of a Novel Class of HIV-1 Protease Inhibitors. J. Med. Chem. 2011, 54, (20), 7176-7183.

Ashit K. Ganguly; Sesha S. Alluri; Chih-Hung Wang; Alyssa Antropow; Alex White; Danielle Caroccia; Dipshikha Biswas; Eunhee Kang; Li-Kang Zhang; Steven S. Carroll; Christine Burlein; John Fay; Peter Orthd, Corey Strickland.Structural optimization of cyclic sulfonamide based novel HIV-1 protease inhibitors to picomolar affinities guided by X-ray crystallographic analysis. Tetrahedron. 2014, 70, (18), 2894-2904.

GHS Gefahren- und Sicherheitshinweise

Gefahrenhinweise (EU): H314-H318-H226

Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapour.

Sicherheitshinweise: P210-P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Weitere Referenzen

Gefahrenklasse
8
Verpackungsgruppe
II
Harmonized Tariff Code
2904.90
TSCA
No

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Kürzlich angesehen

Chemikalien

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Metalle und Stoffe

Katalysatoren

Forschungs- und Laborbedarf