I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
Benzodioxoles are compounds which have an aromatic ring and are a heterocyclic compound containing the methylenedioxy functional group. They are also referred to as 1,2-methylenedioxybenzenes. Benzodioxoles are prepared by reacting catechol derivatives with disubstituted halomethanes. Some of the well known compounds of benzodioxole series are 1,3-Benzodioxole, Safrole and Piperonal.
Benzodioxoles are employed in gemological simulant detection and further in the manufacture of perfumes (McGinty, D.; Letizia, C. S.; Api, A. M. Fragrance material review on 1,3-benzodioxole-5-propanol, alpha-methyl-, 5-acetate. Food Chem. Toxicol. 2012, 50, S330-S332) and pharmaceuticals. A number of endothelin receptor antagonists contain the benzodioxole skeleton. Furthermore, benzodioxole compounds can function as aromatic hydrocarbon responsive receptors (AHR). Safrole is a naturally occurring benzodioxole pesticide that is present in a small amount in all plants. The benzodioxole ring system has been encountered in naturally occurring and synthetic molecules possessing biological activity.