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Tri-tert-butylphosphine is used primarily in the preparation of mono- and bidentate phosphine ligands in metal complexes for catalytic chiral asymmetric hydrogenations and other asymmetric reactions as well as transition metal coupling reactions. This reagent is also used in the preparation of other phosphines in catalytic polymerization reactions.
Hazard Statements: H250-H252-H314-H318
Catches fire spontaneously if exposed to air. Self-heating in large quantities; may catch fire. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P210-P303+P361+P353-P305+P351+P338-P405-P422a-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Store contents under inert gas. Dispose of contents/container in accordance with local/regional/national/international regulations.