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15663-27-1 - cis-Diamminedichloroplatinum(II), Pt 64.5% min - Cisplatin - 10471 - Alfa Aesar

10471 cis-Diamminedichloroplatinum(II), Pt 64.5% min

CAS Number
15663-27-1
Synonyms
Cisplatin

Size Price ($) Quantity Availability
0.25g 75.30
1g 271.00
5g 1160.00
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cis-Diamminedichloroplatinum(II), Pt 64.5% min

MDL
MFCD00011623
EINECS
239-733-8

Chemical Properties

Formula
Cl2H6N2Pt
Formula Weight
300.06
Form
Micro Crystals
Melting point
270° dec.
Solubility
Soluble in DMF. Insoluble in most common solvents

Applications

Being a potent anticancer agent that blocks DNA synthesis, the pharmaceutical compositions are used in chemotherapy. First member of platinum-containing anti-cancer drugs.

Notes

Special handling precautions required. View MSDS prior to purchase. MSDS are available online at www.alfa.com

Literature References

Dasari, S.; Tchounwou, P. B. Cisplatin in cancer therapy: Molecular mechanisms of action. European J. Pharmacol. 2014, 740, 364-378.

Kitagawa, R.; Katsumata, N.; Shibata, T.; Kamura, T.; Kasamatsu, T.; Nakanishi, T.; Nishimura, S.; Ushijima, K.; Takano, M.; Satoh, T.; Yoshikawa, H. Paclitaxel Plus Carboplatin Versus Paclitaxel Plus Cisplatin in Metastatic or Recurrent Cervical Cancer: The Open-Label Randomized Phase III Trial JCOG0505. J. Clin. Oncol. 2014, 58, 4391.

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H315-H319-H334-H317-H350-H335

Fatal if swallowed. Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. May cause cancer. May cause respiratory irritation.

Precautionary Statements: P201-P301+P310a-P308+P313

Obtain special instructions before use. IF SWALLOWED: IF exposed or concerned: Get medical advice/attention.

Other References

Merck
14,2317
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2843.90
TSCA
Yes
RTECS
TP2450000

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