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Being a potent anticancer agent that blocks DNA synthesis, the pharmaceutical compositions are used in chemotherapy. First member of platinum-containing anti-cancer drugs.
Dasari, S.; Tchounwou, P. B. Cisplatin in cancer therapy: Molecular mechanisms of action. European J. Pharmacol. 2014, 740, 364-378.
Kitagawa, R.; Katsumata, N.; Shibata, T.; Kamura, T.; Kasamatsu, T.; Nakanishi, T.; Nishimura, S.; Ushijima, K.; Takano, M.; Satoh, T.; Yoshikawa, H. Paclitaxel Plus Carboplatin Versus Paclitaxel Plus Cisplatin in Metastatic or Recurrent Cervical Cancer: The Open-Label Randomized Phase III Trial JCOG0505. J. Clin. Oncol. 2014, 58, 4391.
Hazard Statements: H300-H315-H319-H334-H317-H350-H335
Fatal if swallowed. Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. May cause cancer. May cause respiratory irritation.
Precautionary Statements: P201-P301+P310a-P308+P313
Obtain special instructions before use. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF exposed or concerned: Get medical advice/attention.