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Tetra-n-butylammonium phosphate is used as a counter-ion in ion-pair reagent in high-performance liquid chromatography for the simultaneous determination of chlorpheniramine and maleate of water-soluble vitamins. It acts as a phase transfer catalyst. Further, it is used as a buffering reagent in HPLC. In addition to this, it is used as a mobile phase additive in two-dimensional reversed-phase high-performance thin-layer chromatography for the separation of chenodeoxycholic acid and deoxycholic acid.
Jeffrey, J. L.; Terrett, J. A.; MacMillan, D. W. C. O-H hydrogen bonding promotes H-atom transfer from α C-H bonds for C-alkylation of alcohols. Science 2015, 349 (6255), 1532-1536.
Lunau, N.; Seelhorst, K.; Kahl, S.; Tscherch, K.; Stacke, C.; Rohn, S.; Thiem, J.; Hahn, U.; Meier, C. Fluorescently Labeled Substrates for Monitoring alpha1, 3-Fucosyltransferase IX Activity. Chem. Eur. J. 2013, 19 (51), 17379-17390.
Hazard Statements: H500
May form combustible dust concentrations in air