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2-Butanone is used as a solvent and for extractions in the pharmaceutical industry. 2-butanone acts as oxidant for the iridium-catalyzed oxidations of primary alcohols. It is useful for the catalytic transfer hydrogenation on MgO. It is used as a mobile phase in High Performance Liquid Chromatography.
Suzuki, T.; Morita, K.; Tsuchida, M.; Hiroi, K. Iridium-Catalyzed Oppenauer Oxidations of Primary Alcohols Using Acetone or 2-Butanone as Oxidant. J. Org. Chem. 2003, 68 (4), 1601-1602.
Szollosi, G.; Bartok, M. Catalytic transfer hydrogenation of 2-butanone on MgO. New active surface sites generated by treatment with chloroform. Catal. Lett. 1999, 59 (2-4), 179-185.
Hazard Statements: H225-H319-H336-H373
Highly flammable liquid and vapour. Causes serious eye irritation. May cause drowsiness or dizziness. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P314-P337+P313-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. Get medical advice/attention if you feel unwell. If eye irritation persists: Get medical advice/attention. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant