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Malonic acid is used to prepare barbiturates. Its derivative diethylmalonate is used in Knoevenagel condensation reactions as well as reacts with acetone to form Meldrum's acid. It is used to control acidity, preservative additive for foods and as an excipient in pharmaceutical formulation. It acts as a precursor to polyesters and as an active component in alkyd resins. Further, it is used as a building block in chemical synthesis. In addition to this, it is used to prepare starch-based resin.
Pardo, F.; Rosas, J. M.; Santos, A.; Romero, A. Remediation of soil contaminated by NAPLs using modified Fenton reagent: application to gasoline type compounds. J. Chem. Technol. Biotechnol. 2015, 90 (4), 754-764.
Tsaplev, Y. B.; Vasilev, R. F.; Trofimov, A. V. Chemiluminescence in reactions of manganese(III) reduction by lactic acid: Two-electron mechanism of chemiexcitation. High Energy. Chem. 2015, 49 (5), 316-321.
Hazard Statements: H302+H332-H315-H318-H335
Harmful if swallowed. Harmful if inhaled. Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant