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[Gd(DO3A-Pr-ATP)(H2O)2] was synthesized by the reaction of DO3A-Pr-ATP with gadolinium(iii) perchlorate hydrate in water. Gadolinium(III) chelates approved by FDA for human imaging.
C. Allen Chang,; Harry G. Brittain,; Joshua Telser,; Michael F. Tweedle. pH dependence of relaxivities and hydration numbers of gadolinium(III) complexes of linear amino carboxylates . Inorg. Chem.. 1990 , 29(22), 4468-4473.
S. James Ratnakar,; Vedhamonickom Alexander. Synthesis and Relaxivity Studies of a Gadolinium(III) Complex of ATP-Conjugated DO3A as a Contrast Enhancing Agent for MRI . European Journal of Inorganic Chemistry. 2005, 2005 (19), 3918-3927.
Hazard Statements: H271-H315-H319-H335
May cause fire or explosion; strong oxidizer. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P210-P220-P221-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep/Store away from clothing/combustible materials. Take any precaution to avoid mixing with combustibles. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant